A Neural-CBR System for Real Property Valuation

In recent times, the application of artificial intelligence (AI) techniques for real property valuation has been on the increase. Some expert systems that leveraged on machine intelligence concepts include rule-based reasoning, case-based reasoning and artificial neural networks. These approaches have proved reliable thus far and in certain cases outperformed the use of statistical predictive models such as hedonic regression, logistic regression, and discriminant analysis. However, individual artificial intelligence approaches have their inherent limitations. These limitations hamper the quality of decision support they proffer when used alone for real property valuation. In this paper, we present a Neural-CBR system for real property valuation, which is based on a hybrid architecture that combines Artificial Neural Networks and Case- Based Reasoning techniques. An evaluation of the system was conducted and the experimental results revealed that the system has higher satisfactory level of performance when compared with individual Artificial Neural Network and Case- Based Reasoning systems

Assessing the performance of global solar radiation empirical equations in Sokoto, Nigeria using meteorological parameters

In this study, the meteorological parameters measured in Sokoto (12.55o N, 5.15o E) for a period of 10 years (2005- 2014) were obtained from the Nigerian Meteorological Agency Sultan Abubakar III International Airport, Sokoto state. The data used include Gunn-Bellani solar radiation, sunshine hour duration, maximum and minimum temperatures, which were analyzed using modified Angstrom models to estimate the monthly mean global solar radiation in Sokoto. Four statistical methods have been used in order to evaluate the results namely; Mean Bias Error (MBE), Mean Percentage Error (MPE), Root Mean Square Error (RMSE) and T-statistic. The standard error (SE) and coefficient of determination (R2) were also obtained for each model. Based on the result obtained models 4 & 5 gave a lower RMSE, and R2 approaches unity, which indicates that there is a good agreement between measured and estimated global solar radiation.Keywords: coefficient of determination, solar radiation, sunshine hours, meteorological parameters, temperatur

Predictors of vaccine management practices among primary healthcare workers (PHCWs) in Ilorin, North Central Nigeria

Objective: Worldwide, vaccines are becoming more expensive as new ones are being introduced to the immunization schedule. Inspite of this, researches have revealed poor vaccine management practices among health workers. This study aimed to determine the predictors of vaccine management practices among PHCWs providing routine immunization services in static health facilities in Ilorin, north central Nigeria.Methods: This quasi-experimental study was conducted among 216 intervention and 241 control groups of PHCWs using multi stage sampling technique; pretested questionnaire and an observational checklist. Data were analyzed using EPI-INFO software package. Level of significance was predetermined at a p-value of less than 0.05.Results: The mean age of study respondents was 38.5 ± 9.5 years. Factors having positive influence on vaccine management practices include prior training exposure (p = 0.001), years of experience in immunization (p = 0.012) and baseline knowledge of vaccine management (p = 0.015). In addition, regularity of supervisory visit (0.008), adequacy/regularity of vaccine supply (p = 0.001), vaccine 'bundling' (p = 0.013) and type of health facility (p = 0.005) positively influenced respondents' vaccine management practices. However, basic qualification of health workers (p = 0.096) and availability of data tools (p = 0.628) had no significant influence on respondents' vaccine management practices.Conclusion: Training exposure and years of experience in routine immunization have positive influence on vaccine management practices of PHCWs. On-the-job supervision of health workers should be conducted at least bi-annually.Keywords: Predictors, Vaccine management practices, PHCW

Knowledge of blood donation among adults in north-central Nigeria

Background: About half of the population in Nigeria is medically fit for blood donation but only four in one thousand are voluntary donors. The low level of blood donation has been attributed to poor knowledge, misconceptions, myths, bias, poverty, fear, malnutrition among the population. Therefore, this study assessed the knowledge of blood donation among adults in two selected North Central States of Nigeria.Methods: It was a descriptive cross-sectional study. A total of 3104 respondents comprising of adults between 18 and 60 years were involved in the study. A multistage sampling technique was used and the research tool was interviewer-administered questionnaire. The data generated were entered into the computer and subjected to appropriate statistical analysis using EPI INFO computer software package (version 3.5.3). Pearson Chi Square (χ2) was used to test statistical significance and p-value was set at < 0.05.Results: Majority of the respondents 2565 (82.5%) knew that blood donation save lives. More than three-quarters, 2468 (79.5%), knew where to go for voluntary blood donation. About one-third, (37.1%), demonstrated good knowledge of voluntary blood donation. Older respondents (>60 years) had poor knowledge of blood transfusion compared with younger age groups (p<0.001). Respondents’ occupation and educational status were significantly associated with knowledge of blood transfusion (p<0.001)Conclusion: Periodic awareness programme on voluntary blood donation in rural and urban areas across Nigeria is needed. In addition, sensitization of the informal sector on the significance of non-remunerated voluntary blood donation should be given priority.Keywords: Knowledge, Blood, Donation, North-Central, Nigeri

Effect of training on knowledge, attitude and practice of safety measures among battery chargers in Ilorin metropolis

Objective: Good knowledge of safety measures against hazards of lead-acid battery work is important in the control of the work-related health problems. The study assessed the effects of training on knowledge, attitude and practice of safety measures among battery chargers in Ilorin, Nigeria.Methods: The study was a quasi-experimental (non-randomized) study with pretest and post-test design. A total of 107 battery chargers were recruited each for intervention and control group. The study group was offered training on occupational safety measures while the control group did not have training at this stage. Post intervention data was collected 12 weeks after the pre-intervention. Multistage sampling technique was used to select 214 registered battery chargers working in Ilorin in to the study. Data obtained through interviewer-administered questionnaires were analysed using SPSS version 16 software.Results: Less than one-fifth (15.9%) of the study group had good knowledge of hazards relating to battery which increased significantly to more than three-quarters (76.2%) post-intervention. The majority (85.0%) of the study group and (86.0%) of the control group had positive attitude towards safety measures pre-intervention. There was no significant improvement in attitude post intervention. The safety practice of less than one-tenth (6.5%) of the study group was rated good pre-intervention which increased significantly to almost one-fifth (17.8%) post-intervention. There was no significant improvement in the Kwowledge, attidude or practice of safety measures among the control group post intervention.Conclusion: Association of the battery chargers should organize in conjunction with the health institutions training of their members on hazards prevention and safety practices.Keywords: Training, battery, safety measures, workers, Ilori

Extraction of Chrysophyllum albidum Seed Oil: Optimization and Characterization

This work presents the result of the optimization of extraction of oil from Chrysophyllum albidum seed using ethanol as solvent. A 23 factorial designs with replication was employed to study the effect particle size, time, and temperature of extraction. The oil yield from extraction was 12.70 – 16.85 % with the optimal yield of 16.85 % at particle size of 500 µm, temperature of 55 0 C, and a time of 6 hours. Characterizations of the oil reveal a Saponification value of 228.4mgKOH/g, iodine value of 30 gI2 /100g, peroxide value of 1.45 meq/kg, acid value of 2.52 mgKOH/g. The oil extracted from this seed can be effectively used for variety of domestic and industrial application such as the making of paint, candles, soap and biodiesel. Keywords: Optimization, Characterization, Chrysophyllum albidum, Oi

Determinants of voluntary blood donation among adults in communities of north central region of Nigeria

Objective: The collection of blood from voluntary, non-remunerated blood donors is an important measure for ensuring the safety, quality, availability and accessibility of blood. The study assessed factors affecting voluntary blood donation in North-central zone, Nigeria.Methods: The study design was descriptive cross-sectional, data was collected using a pre-tested interviewer administered questionnaire from 3104 respondents using multistage sampling technique. Data was analyzed using EPI INFO computer software package (version 3.5.3). Level of significance was pre-determined at p-value < 0.05 at a confidence level of 95%.Results: Respondents with good knowledge of voluntary blood donation had better practice of voluntary blood donation. Younger age groups were 8 times more likely to donate blood voluntarily than older respondents. Yoruba ethnic groups are 1.5 times more likely to donate blood than other ethnic groups.Conclusion: For Nigeria and other developing countries at large to achieve 100% voluntary blood donation drive by year 2020, it is critical to change the blood donation culture from replacement to that of volunteerism through more effective communication and mobilization of donors. These efforts must be rendered more methodical and accomplished through a wider range of strategies.Keywords: Determinants, voluntary, blood, donation, Nigeri

Traditional eye medication: A rural-urban comparison of use and association with glaucoma among adults in Ilorin-west Local Government Area, North-Central Nigeria

Background: Globally, the last two decades witnessed increase in the use of  Traditional Eye Medication (TEM); and its use worsens the prognosis of visual outcome. This study assessed and compared the use of TEM and its association with glaucoma among adults in selected rural and urban communities of Ilorin-west Local Government Area, North-Central Nigeria.Methodology: This was a comparative cross-sectional study. Respondents were selected using multi-stage sampling technique. Interviewer-administered structured questionnaire, and clinical report form were used to collect data. Data were analyzed using SPSS version 15. Level of statistical significance was set at p<0.05.Results: A higher proportion of the rural, 174 (38.7%) than the urban, 111 (24.7%) respondents knew about TEM (p<0.001). More of the rural, 83 (18.4%) than the urban, 78 (17.3%) respondents had ever used TEM (p=0.664). TEM known to the respondents in rural versus urban areas included camphor (47.1% vs 28.8%), personal urine (3.5% vs 2.7%) and salt-sugar solution (1.7% vs 14.4%) among others. There exists an association between the use of traditional eye medication and presence of glaucoma within rural (p=0.011) and urban (p<0.001) areas.Conclusion: The use of TEM among the respondents was associated with glaucoma. While the association between glaucoma and uptake of TEM may not be causal, it provides a window of thought for further researches. There is need to strengthen awareness on the dangers of using TEM in the communities. Regular  community-based eye screening involving measurement of intraocular pressure will be useful in early detection of glaucoma.Keywords: Traditional eye medication; Glaucoma; Rural-Urban; Nigeri

Possible Impact of Co-infections of Tuberculosis and Malaria on the CD4+ Cell Counts of HIV Patients in Nigeria

Background: This study focused on evaluating the possible impact of co-infections of tuberculosis and malaria on the CD4+ cell counts in HIV infected subjects. Methods: This is a cross sectional study. The subjects were drawn from three hospitals and a blood bank in LagosState. After due consent, blood samples were obtained from 69 subjects with single infections (HIV, TB, and Malaria), 34 subjects with multiple infections (HIV/Malaria, HIV/TB, Malaria/TB, HIV/TB/Malaria) and 24 blood donors (controls). The CD4+ cell counts of all the 127 blood samples were estimated using a FACS count. Results: Data obtained were analysed and a comparison of the results showed that the median CD4+ counts in all groups of subjects with HIV infections (whether single or co-infection) were similar and significantly lower than the median counts for the healthy control group as well as groups without HIV infection (malaria, TB and malaria/TB). Conclusion: Overall data further confirmed the progressive depletion of CD4+ cells in HIV infection while co-infections with TB and malaria did not have any impact on the CD4+ cells of HIV infected subjects. A larger prospective study is needed.Fond: Cette \ue9tude a \ue9t\ue9 consacr\ue9e \ue1 l'\ue9valuation de l'impact possible de co-infections de tuberculose et le paludisme sur les comptes de cellule CD4+ des sujets infect\ue9s du VIH. M\ue9thode: Ceci est une \ue9tude transversale. Les sujets ont \ue9t\ue9 choisis de trois diff\ue9rents h\uf4pitaux et une banque du sang dans l'Etat de Lagos. Apr\ue8s le consentement n\ue9cessaire, les \ue9chantillons de sang ont \ue9t\ue9 obtenus de 69 sujets avec les mono-infections (VIH, TB, et le Paludisme), 34 sujets avec les infections multiples (le VIH/PALUDISME, LE VIH/TB, LE Paludisme/TB, VIH/TB/le Paludisme) et 24 donneurs de sang (les contr\uf4les). les comptes de cellule CD4+ de tous les 127 \ue9chantillons de sang ont \ue9t\ue9 estim\ue9s utilisant une compte FACS. R\ue9sultats: les donn\ue9es obtenues ont \ue9t\ue9 analys\ue9es et une comparaison des r\ue9sultats a d\ue9montr\ue9 que le m\ue9dian des comptes CD4+ dans tous les groupes de sujets avec les infections de VIH (soit mono ou co-infection) \ue9taient similaires et significativement plus bas que les comptes m\ue9dianes pour le groupe de contr\uf4le sain de m\ueame que les groupes sans l'infection de VIH (le paludisme, TB et le paludisme/TB). Conclusion: les donn\ue9es g\ue9n\ue9rales ont confirm\ue9 le plus l'\ue9puisement progressif des cellules CD4+ dans l'infection de VIH pendant que les co-infections avec TB et le paludisme n'ont pas eu aucun impact sur les cellules CD4+ des sujets infect\ue9s de VIH. Une plus profonde \ue9tude sera n\ue9cessaire

High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive Ewing sarcoma

Ewing sarcoma (EwS) is an aggressive cancer displaying an undifferentiated small-round-cell histomorphology that can be easily confused with a broad spectrum of differential diagnoses. Using comparative transcriptomics and immunohistochemistry (IHC), we previously identified BCL11B and GLG1 as potential specific auxiliary IHC markers for EWSR1-FLI1-positive EwS. Herein, we aimed at validating the specificity of both markers in a far larger and independent cohort of EwS (including EWSR1-ERG-positive cases) and differential diagnoses. Furthermore, we evaluated their intra-tumoral expression heterogeneity. Thus, we stained tissue microarrays from 133 molecularly confirmed EwS cases and 320 samples from morphological mimics, as well as a series of patient-derived xenograft (PDX) models for BCL11B, GLG1, and CD99, and systematically assessed the immunoreactivity and optimal cut-offs for each marker. These analyses demonstrated that high BCL11B and/or GLG1 immunoreactivity in CD99-positive cases had a specificity of 97.5% and an accuracy of 87.4% for diagnosing EwS solely by IHC, and that the markers were expressed by EWSR1-ERG-positive EwS. Only little intra-tumoral heterogeneity in immunoreactivity was observed for differential diagnoses. These results indicate that BCL11B and GLG1 may help as specific auxiliary IHC markers in diagnosing EwS in conjunction with CD99, especially if confirmatory molecular diagnostics are not available